Active cytomegalovirus retinitis after the start of antiretroviral therapy

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Cytomegalovirus retinitis in the era of highly active antiretroviral therapy.

Cytomegalovirus (CMV) is a common opportunistic infection in individuals with AIDS. Moreover, CMV retinitis represents a significant portion of end-organ disease in patients with CMV and AIDS. Prior to the advent of highly active antiretroviral therapy (HAART), almost one-third of people with AIDS developed CMV retinitis during their lifetime. Although effective therapies for CMV infection had ...

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Cytomegalovirus retinitis after the initiation of highly active antiretroviral therapy: a 2 year prospective study.

BACKGROUND/AIMS There have been several recent reports suggesting that the natural history of cytomegalovirus retinitis (CMVR) has been significantly modified with the development of highly active antiretroviral therapy (HAART). This 2 year prospective cohort study assesses the effect of HAART on the incidence and progression of CMV retinitis in patients with CD4 cell counts below 50 cells x10(...

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Long term visual outcome of patients with cytomegalovirus retinitis treated with highly active antiretroviral therapy.

BACKGROUND Healed cytomegalovirus (CMV) retinitis in the setting of highly active antiretroviral therapy (HAART) is complicated by inflammatory sequelae and vision loss. AIM To determine the long term visual outcome of AIDS patients with CMV retinitis who received HAART. METHODS 90 eyes of 63 consecutive AIDS patients with extramacular CMV retinitis were studied prospectively. RESULTS Imm...

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Cystoid macular oedema in patients with AIDS and cytomegalovirus retinitis on highly active antiretroviral therapy.

EDITOR,—Between 16% and 40% of patients with AIDS develop cytomegalovirus retinitis (CMVR). 2 This typically presents when the CD4+ count drops below 75 cells/μl. Visual loss is usually due to retinal detachment, macular or optic nerve infection, or vascular occlusion. Typically a minimal inflammatory response is mounted. Patients with CMVR not associated with HIV infection may develop a vitrit...

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LETTERS TO THE EDITOR Cystoid macular oedema in patients with AIDS and cytomegalovirus retinitis on highly active antiretroviral therapy

EDITOR,—Between 16% and 40% of patients with AIDS develop cytomegalovirus retinitis (CMVR). 2 This typically presents when the CD4+ count drops below 75 cells/μl. Visual loss is usually due to retinal detachment, macular or optic nerve infection, or vascular occlusion. Typically a minimal inflammatory response is mounted. Patients with CMVR not associated with HIV infection may develop a vitrit...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 2018

ISSN: 0007-1161,1468-2079

DOI: 10.1136/bjophthalmol-2018-312406